Parkinson's disease: in vivo assessment of disease progression using positron emission tomography.
Identifieur interne : 002968 ( Main/Exploration ); précédent : 002967; suivant : 002969Parkinson's disease: in vivo assessment of disease progression using positron emission tomography.
Auteurs : Wing Lok Au [Canada] ; John R. Adams ; André R. Troiano ; A Jon StoesslSource :
- Brain research. Molecular brain research [ 0169-328X ] ; 2005.
English descriptors
- KwdEn :
- Animals, Brain (diagnostic imaging), Disease Progression, Dopamine, Dopamine Plasma Membrane Transport Proteins, Humans, Membrane Glycoproteins, Membrane Transport Proteins, Models, Neurological, Nerve Tissue Proteins, Parkinson Disease (diagnostic imaging), Positron-Emission Tomography, Vesicular Biogenic Amine Transport Proteins.
- MESH :
- chemical : Dopamine, Dopamine Plasma Membrane Transport Proteins, Membrane Glycoproteins, Membrane Transport Proteins, Nerve Tissue Proteins, Vesicular Biogenic Amine Transport Proteins.
- diagnostic imaging : Brain, Parkinson Disease.
- Animals, Disease Progression, Humans, Models, Neurological, Positron-Emission Tomography.
Abstract
Over the past two decades, positron emission tomography (PET) has provided valuable insights into the mechanisms of nigrostriatal degeneration in Parkinson's disease (PD). Furthermore, it allows the in vivo assessment of disease progression and the evaluation of treatment interventions. In this review, we shall discuss some of the issues and concerns that arise with the use of PET as a surrogate marker of disease progression in Parkinson's disease.
DOI: 10.1016/j.molbrainres.2004.09.028
PubMed: 15790527
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Over the past two decades, positron emission tomography (PET) has provided valuable insights into the mechanisms of nigrostriatal degeneration in Parkinson's disease (PD). Furthermore, it allows the in vivo assessment of disease progression and the evaluation of treatment interventions. In this review, we shall discuss some of the issues and concerns that arise with the use of PET as a surrogate marker of disease progression in Parkinson's disease.</div>
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